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FORSCHUNGSBERICHT 1999-2001 | INDEX
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Institut für Theoretische Kernphysik
Institut für Anorganische Chemie
| Forschungsbericht
Mathematisch-Naturwissenschaftliche Fakultät
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Allgemeine Angaben:
Gerhard-Domagk-Straße 1, 53121 Bonn
Telefon: 0228 / 73-2650
WWW: http://www.chemie.uni-bonn.de
Archut A, Vögtle F
Dendritic Molecules - Historic Development and Future Applications
H.S. Nalwa (ed.), Handbook of Nanostructured Materials and Nanotechnology, Vol. 5: Organics, Polymers, and Biological Materials, Academic Press 2000, 333-374
Balzani V, Ceroni P, Gestermann S, Gorka M, Kauffmann C, Maestri M, Vögtle F
Eosin Molecules Hosted into a Dendrimer Which Carries Thirty-Two Dansyl Units in the Periphery: A Photophysical Study
Chem. Phys. Chem. 2000, 4, 224-227
Balzani V, Ceroni P, Gestermann S, Gorka M, Kauffmann C, Vögtle F
Effect of protons and metal ions on the fluorescence properties of a polylysin dendrimer containing twenty four dansyl units
J. Chem. Soc., Dalton Trans. 2000, 3765-3771
Balzani V, Ceroni P, Gestermann S, Kauffmann C, Gorka M, Vögtle F
Dendrimers as fluorescent sensors with signal amplification
Chem. Commun. 2000, 853-854
Bär J, Linke T, Ferlinz K, Neumann U, Schuchman EH, Sandhoff K
Molecular Analysis of Acid Ceramidase Deficiency in Patients With Farber Disease
Human Mutation 17:99-209
Bernardo K, Oleg K, Wiegmann K, Kreder D, Micheli M, Schäfer R, Sickmann A, Schmidt W E, Schröder JM, Meyer HE, Sandhoff K, Krönke M
Purification and Chracterization of a Magnesium-dependent Neutral Sphingomyelinase from Bovine Brain
J. Biol.Chem. 275, 11, 7641-7647
Bierfreund U, Kolter T, Sandhoff K
Sphingolipid hydrolases and activator proteins
Methods in Enzymology Vol. 311, 2000, 255-276
Blind, M., Kolanus, W., Famulok, M.
Cytoplasmic RNA modulators of an inside-out signal-transduction cascade
Proc. Natl. Acad. Sci. USA. 96, 3606-3610
Böhme R., Breitmaier E.
2,3-Diazaporphyrins Bearing two Nitrogen Atoms at the Periphery
Synthesis, 1999, 2096-2102
Boomgaarden W, Vögtle F, Nieger M , Hupfer H
Broad Molecular Ribbons of Nanometer Size Composed of Biphenyl Units
Chem.Eur.J. 1999, 5, No. 1, 345-355
Bräse S
Intramolecular Transition-Metal Catalyzed Cyclizations of Electron Rich Chloroarenes
Tetrahedron Lett. 1999, 40, 6757-6759
Bräse S
Synthesis of Bis(enolnonaflates) and their 4-exo-trig-Cyclizations by Intramolecular Heck Reactions
Synlett 1999, 1654-1656
Bräse S
New linkers for solid phase organic chemistry. Multidirectional (multifunctional), backbone amide, and traceless linker
Chim. Oggi 2000, 18 (9), 14-19
Bräse S
Trendberichte "Kombinatorische Chemie"
Nachr. Tech. Lab. 2001, 311-315
Bräse S, Dahmen S
Traceless Linkers - Only Disappearing Links in Solid-Phase Organic Synthesis?
Chem. Eur. J. 2000, 6, 1899-1905
Bräse S, Dahmen S, Pfefferkorn M
Solid-Phase Synthesis of Urea and Amide Libraries Using the T2 Triazene Linker
J. Comb. Chem. 2000, 2, 710-715
Bräse S, Heuts J, Dahmen S
Solid-phase Synthesis of Substituted Cinnolines by a Richter Type Cleavage Protocol
Tetrahedron Lett. 1999, 40, 6201-6203
Bräse S, Köbberling J, Enders D, Wang M, Lazny R, Brandtner S
Triazenes as Robust and Simple Linker for Amines in Solid-Phase Organic Synthesis
Tetrahedron Lett. 1999, 40, 2105-2108
Bräse S, Schroen M
Eine neue effiziente Abspaltungs-Kreuzkupplungs-Strategie für Festphasenreaktionen - Ein Baukastensystem für die Kombinatorische Chemie (Efficient cleavage - Cross-coupling strategy for solid-phase synthesis - A modular building system for combinatorial chemistry)
Angew. Chem. 1999, 111, 1139-1142; Angew. Chem. Int. Ed. 1999, 38, 1071-1073
Braun O, Hünten A, Vögtle F
Template Synthesis of Rotaxanes with Carbamate-Linked Axles
J. Prakt. Chem. 1999, 341, No. 6, 542-547
Breitmaier E.
Terpene
B. G. Teubner Stuttgart, Leipzig 1999; ISBN 3-519-03548-0
Breitmaier E., Jung G.
Organische Chemie
Georg Thieme Verlag Stuttgart 2001; ISBN 3-13-541504-X
Ceroni P, Vicinelli V, Maestri M, Balzani V, Müller WM, Müller U, Hahn U, Osswald F, Vögtle F
Dendrimers with a 4,4'-bipyridinium core and electron-donor branches. Electrochemical and spectroscopic properties
New J. Chem. 2001, 25, 989-993
Chartroux C, Krueger-Rambusch T, Gloe K, Bozkurt F, Horn M, Ibach S, Vögtle F
Solvent extraction studies of silver by spherical ligands incorporating aromatic subunits
Czech. J. Phys. 49, 1999, 709-714
Chartroux C, Rambusch T, Gloe K, Horn M, Vögtle F
Darstellung und Selektive Komplexbildung von Bisorganylsulfiden auf [2.2.2]Paracyclophan-Basis
J. Prakt. Chem. 1999, 341, 8, 778-784
Chartroux C, Wichmann K, Goretzki G, Rambusch T, Gloe K, Müller U, Müller WM, Vögtle F
Preorganized Complexing Agents as a Tool for Selective Solvent Extraction Processes
Ind. Engl Chem. Res. 2000, 39, 3616-3624
Dahmen S, Bräse S
Das erste stabile Diazoniumion an der festen Phase - Untersuchungen zur Stabilität und Verwendung als Linker und Scavenger in der Festphasenchemie (The First Stable Diazonium Ion on Solid Support - Investigations on Stability and Usage as Linker and Scavenger in Solid-Phase Organic Synthesis)
Angew. Chem. 2000, 112, 3827-3830; Angew. Chem. Int. Ed. 2000, 39, 3681-3683
Dahmen S, Bräse S
A Novel Solid Phase Synthesis of Highly Diverse Guanidines: Reactions of Primary Amines Attached to the T2* Linker
Org. Lett. 2000, 2, 3563-3565
Dahmen S, Bräse S
[2,2]Paracyclophane-based N,O-Ligands in Alkenylzinc Additions to Aldehydes
Org. Lett. 2001, 4119-4122
Dahmen S, Bräse S
Preparation of planar chiral amino alcohols based on the [2.2]paracyclophane backbone
Tetrahedron Asymm. 2001, 12, 2845-2850
Dahmen S, Bräse S
Combinatorial Methods for the Discovery and Optimisation of Homogeneous Catalysts.
Synthesis 2001, 1431-1149
Dell, A., Famulok, M., Imperiali, B.
Biopolymers. Chemical and biological approaches for understanding form and function
Curr Opin Chem Biol. 4, 599-601.
de Meijere A, Bräse S
Palladium-Catalyzed Cross-Coupling Reactions - A Personalized Account
Chemistry for the 21st Century: Transition Metal-catalysed Reactions: Hrsg.: S. Murahashi, S. G. Davies, Blackwell Sciences, 1999, S. 99-131
de Meijere A, Bräse S
Palladium in Action: Domino and Cascade Coupling Reactions for the Efficient Construction of Complex Organic Molecules
J. Organomet. Chem. 1999, 576, 88-110
de Meijere A, Bräse S
Palladium in Action: Domino and Cascade Coupling Reactions for the Efficient Construction of Complex Organic Molecules
Perspectives in Organopalladium Chemistry for the 21st Century, Elsevier-Publications, Hrsg.: J. Tsuji, 1999.
de Meijere A , Nüske H, Es-Sayed M, Labahn T, Schroen M, Bräse S
Neue effiziente Mehrkomponenten-Reaktionen unter C-C-Knüpfung zur kombinatorischen Anwendung in flüssiger und an fester Phase (New efficient multicomponent reactions with C-C coupling for combinatorial application in liquid and on solid phase)
Angew. Chem. 1999, 111, 3881-3884; Angew. Chem. Int. Ed. 1999, 38, 3669-3672
Djukic J, Maisse-Francois A, Pfeffer M, Dötz KH, De Cian A, Fischer J
Organometallic Helices: The Mechanism of Formation of "Metallospiralenes"
Organometallics 19, 2000, 5484-5499
Djukic J, Michon C, Maisse-Francois A, Allagapen R, Pfeffer M, Dötz KH, De Cian A, Fischer J
Chiral Metallo-Spiralenes: Helical Molecules Conformationally Stabilised by an Organometalllic Scaffold
Chem Eur J 6, 2000,1064-1077
Djukic JP, Maisse A, Pfeffer M, Dötz KH, Nieger M
Reactions of Organolithium Reagents with Cyclorhenated and Cyclomanganated tricarbonylchromium Complexes: Structural Characterization of a New Benzoyl-rhenate Intermediate an Selective Ortho-Acetylation of tricarbonylchromium Complexes
Organometallics 18, 1999, 2786-2790
Djukic JP, Pfeffer M, Dötz KH
Slackening a chromium carousel with a manganese bridle: selective C isotopic labelling applied to the determination of the steric barrier to rotation a Cr(CO)3 group in a syn-facial hetero-bimetallic (Cr, Mn) cyclohexadienylbenzylidene complex
C R Acad Sci Paris 2, 1999, 403-408
Doering T, Holleran WM, Potratz A, Vielhaber G, Elias PM , Suzuki K, Sandhoff K
Sphingolipid Activator Proteins Are Required for Epidermal Permeability Barrier Formation
J. Biol. Chem. 274, 11038-11045
Doering T, Holleran WM, Potratz A, Vielhaber G, Elias PM, Suzuki K, Sandhoff K
Sphingolipid Activator Proteins Are Required for Epidermal Permeability Barrier Formation
J. Biol. Chem. 274, 11038-11045
Doering T, Proia RL, Sandhoff, K
Accumulation of protein-bound epidermal glucosylceramides in b-glucocerebrosidase deficient type 2 Gaucher mice
FEBS Lett. 447, 167-170
Dötz KH, Böttcher D, Jendro M
Reactions of complex ligands Part 84. Chiral diene-dienophile- functionalized amino-carbene complexes of molybdenum: synthesis an intramolecular Diels-Adler reaction
J Organomet Chem 583,1999, 34-41
Dötz KH, Donaldson WA, Sturm W
Reaction of Alkynes with Tetracarbonyl[Methoxy(2,4-Dimethoxyphenyl)Carbene]Chromium: A formal Synthesis of 7-Methoxyeleutherin
Synthetic Communications 30/20, 2000, 3775-3784
Dötz KH, Gomes da Silva E
Carbohydrate-Modified Fused Pyranosylidene Complexes via Radical Addition of Epoxides to Unsaturated Metal Carbenes
Tetrahedron 56, 2000, 8291-8299
Dötz KH, Jäkel C
From Glycals to Metal Pyranosylidenes: Diastereoselective Additon of Electrophiles to Metal Carbene Enolate Intermediates
Tetrahedron 56,2000, 2167-2173
Dötz KH, Jäkel C, Haase WC
Metal glycosylidenes: novel organometallic tools for C-glycosidation
J Organomet Chem 617-618, 2001, 119-132
Dötz KH, Klumpe M, Nieger M
Chromium Iminoglycosylidenes: Synthesis and Application to Photoinduced C-Glycosidation
Chem Eur J 5, 1999, 691-699
Dötz KH, Koch AW, Weyershausen B, Hupfer H, Nieger M
Spirocyclobutanes via Metal Carbene Facilitated Diastereoselective [2+2]Cycloaddition Reactions of exo-Methylene Oxacyclopentylidene Complexes of Chromium an Tungsten
Tetrahedron 56,2000, 4925-4934
Dötz KH, Otto F, Nieger M
Glucal-derived carbene complexes: synthesis and diastereoselective benzannulation
J Organomet Chem 621, 2001, 77-88
Dötz KH, Paetsch D, Le Bozec H
Activation of sugar-based alcynols at a metal carbonyl template: a metal venyl carbene functionalization of carbohydrates and non-conventional route to organometallic disaccharides
J Organomet Chem 589, 1999, 11-20
Famulok, M.
Oligonucleotide aptamers that recognize small molecules.
Curr. Opin. Struct. Biol. 9, 324-329.
Famulok, M.
RNA and DNA Aptamers.
In: Combinatorial Chemistry. G. Jung (Ed.) Wiley-VCH, 319-333.
Famulok, M., Blind, M., Mayer, G.
Intramers as promising new tools in functional proteomics.
Chem. Biol. 8, 931-939.
Famulok, M., Jenne, A.
Catalysis Based on Nucleic Acid Structures
Top. Curr. Chem. 202, 101-131.
Famulok, M., Kolanus, W.
“Chemistry in Biology“-life sciences future.
Chem. Eng. News 13, 79-80.
Famulok, M., Mayer, G.
Recent developments in aptamer technology. In: Combinatorial Chemistry in Biology.
Current Topics in Microbiology and Immunology (M. Famulok, C.-H. Wong, E.-L. Winnacker, Eds.), Vol. 243, Springer Verlag, Heidelberg, pp. 123-136
Famulok, M.; Jäschke, A.; Wölfl, S.
Optimizing Structure and Function Relationship of Nucleic Acid Molecules.
Microsystem technology: a powerful tool for biomolecular studies (H. P. Saluz, Ed.) Birkhäuser Verlag, Heidelberg, 507-528
Famulok, M.; Mayer, G., Blind, M.
Nucleic Acid Aptamers – From Selection In Vitro to Applications In Vivo.
Acc. Chem. Res. 33, 591-599.
Ferlinz K, Kopal G, Bernardo K, Linke T, Breiden B, Neumann U, Kettenhofen R, Lang F, Schuchman EH, Sandhoff K
Human Acid Ceramidase: Processing, Glycosylation and Lysosomal Targeting
J.Biol.Chem. 276, 35352-60
Ferlinz K, Linke T, Bartelsen O, Weiler M, Sandhoff K
Stimulation of lysosomal sphingomyelin and ceramide degradation by sphingolipid activtor proteins
Chem. Phys. Lipids 102, 1999, 35-43
Feuerbacher N, Vögtle F, Windscheidt J, Poetsch E , Nieger M
Synthesis of Rodlike Dispiro Hydrocarbon Skeletons for New Liquid Crystal Compounds
Synthesis 1999, 1, 117-120
Fischer M, Vögtle F
Dendrimere: vom Design zu Anwendung - ein Fortschrittsbericht; Dendrimers: From Design to Application - A Progress Report
Angew. Chem. 1999, 111/7, 934-955; Angew. Chem. Int. Ed. Engl. 1999, 38/7, 884-905
Furche R, Ahlrichs R, Wachsmann C, Weber E, Sobanski A, Vögtle F, Grimme S
Circular Dichroism of Helicenes Investigated by Time-Dependent Density Functional Theory
J. Am. Chem. Soc. 2000, 122, 1717-1724
Gansäuer, A., Lauterbach, T., Bluhm, H., Noltemeyer, M.
The First Example of a Catalytic Enantioselective Electron Transfer Reaction: Titanocene Catalyzed Enantioselective Formation of Radicals from Epoxides;
Angew. Chem. 1999, 111; 3112; Angew. Chem. Int. Ed. 1999, 111, 2909.
Gansäuer A , Bluhm H
Reagent Controlled Transition Metal Initiated and Catalyzed Reactions
Chem. Rev. 2000, 100, 2771
Gansäuer A, Bluhm H , Lauterbach T
Titanocene Catalyzed Enantioselective Opening of meso-Epoxides
Adv. Synth. Catal. 2001, 343, 785
Gansäuer A, Bluhm H, Pierobon M , Keller M
Conformational Preferences of Titanocene Dichlorides with Ligands Derived from Menthol: Comparison of Structures in Solution and in the Crystal
Organometallics, 2001, 20, 914
Gansäuer A, Pierobon M
Titanocene Catalyzed 5-exo Cyclizations of Epoxides
Synlett 2000, 1357
Gansäuer A, Pierobon M
Opening reactions of Small Rings (Epoxides and Cyclopropanes)
Radicals in Organic Synthesis; Renaud, P.; Sibi, M. P. Eds.; Wiley-VCH: Weinheim; 2001, Vol. 2, 207.
Gansäuer A, Pierobon M, Bluhm H
Control of Diastereoselectivity in Titanocene Catalyzed Cyclizations of Epoxides
Synthesis, 2001, 2500
Gerhardt A, Dötz KH
Chiral quinoid and hydroquinoid [2.2] metacyclophanes via chromium-mediated intramolecular benzannulation
J Organomet Chem 578, 1999, 223-228
Giehl A, Lemm T, Bartelsen O, Sandhoff K, Blume A
Interaction of the GM2-activator protein with phospholipid/ganglioside bilayer membranes and with monolayers at the air/water interface
Eur. J. Biochem. 261, 650-658
Giehl A, Lemm T, Bartelsen, Sandhoff K, Blume A
Interaction of the GM2-activator protein with phospholipid/ganglioside bilayer membranes and with monolayers at the air/water interface
Eur. J. Biochem. 261, 650-658
Grassmé H, Jekle A, Riehle A, Schwarz H, Berger J, Sandhoff K, Kolesnick R, Gulbins, E
CD95 Signaling via Ceramide-rich Membrane Rafts
J.Biol.Chem. (276), 20589-20596
Gravel RA, Kaback MM, Proia RL, Sandhoff K, Suzuki K, Suzuki K
The GM2-gangliosidosis
The Metabolic and Molecular Basis of Inherited Disease, eds. Scriver, Charles, Beaudet, Arthur, L., Sly, William, S., and Valle, David, David Mc Graw Hill, N.Y.,.8th edition, Chapter 153 (2001), 3573-3589
Grimme S, Mennicke W, Vögtle F, Nieger M
Experimental and theoretical studies of a chiral azulenophane: synthesis, structure and circular dichroism spectra of 14,17-dimethyl[2](1,3)azuleno[2]paracyclophane
J. Chem. Soc., Perkin Trans. 2, 1999, 521-527
Gunst K., Seggewies S., Breitmaier E.
New Chiral Macrocyclic Di-imines Containing Tetrapyrroles and Tripyrrane Subunits
Synthesis 2001, 1856-1860
Gutenberger G, Blechert S, Steckhan E
alpha-Cyano-gamma-lactones by photoinduced electron transfer-catalyzed oxidation of alpha-hydroxyalkylsilanes in the presence of alpha-cyano acrylates
Tetrahedron Lett 41(4) 2000, 461-464
Haase WC, Dötz KH
One-Pot Synthesis of N-Unprotected Azacyclopentylidene Comoplexes from their Oxa Analogues
Tetrahedron Lett 1999, 40, 2919-2920
Haase WC, Nieger M, Dötz KH
Furanosylidene and Iminofuranosylidene Complexes: Synthesis by Stoichiometric Olefin Metathesis and Ring-Opening /Mitsunobu-Recyclization Sequence
Chem Eur J 1999, 5, 2014-2024
Haberl U, Steckhan E, Blechert S, Wiest O
Electron-transfer-induced Diels-Alder reactions of indole and exocyclic dienes: Synthesis and quantum-chemical studies
Chem-Eur J 5(10) 1999, 2859-2865
Haberl U, Wiest O, Steckhan E
Ab initio studies of the radical cation Diels-Alder reaction
J Am Chem Soc 121(28) 1999, 6730-6736
Hadrich D, Berthold F, Steckhan E, Bönisch H
Synthesis and characterization of fluorescent ligands for the norepinephrine transporter: Potential neuroblastoma imaging agents
J Med Chem 42(16) 1999, 3101-3108
Heil C, Windscheif GR, Braschohs S, Flörke J, Gläser J, Lopez M, Müller-Albrecht J, Schramm U, Bargon J, Vögtle F
Highly selective sensor materials for discriminating carbonyl compounds in the gas phase using quartz microbalances
Sensors and Actuators B 61 1999, 51-58
Heim C , Affeld A, Nieger M, Vögtle F
Size Complementarity of Macrocyclic Cavities and Stoppers in Amide-Rotaxanes
Helv. Chim. Acta 82, 1999, 746-759
Heim C, Udelhofen D, Vögtle F
Amide-Based Catenanes, Rotaxanes and Pretzelanes
in: J.-P. Sauvage, C. Dietrich-Buchecker (eds.), Molecular Catenanes, Rotaxanes and Knots. A Journey Through the World of Molecular Topology, Wiley-VCH 1999, 177-222
Heinemann T, Bulwin GC, Randall J, Schnieders B, Sandhoff K, Volk HD, Milford E, Gullans SR, Utku N
Genomic organization of the gene coding for TIRC7, a novel Membrane protein essential for T cell activation
Genomics, May 1; 57(3), 398-406
Heinemann T, Bulwin GC, Randall J, Schnieders B, Sandhoff K , Volk HD, Milford E, Gullans S, Utku N
Genomic organization of the gene coding for TIRC7, a novel Membrane protein essential for T cell activation
Genomics, May 1; 57(3), 398-406
Hoffmann P, Sandhoff K, Marsh D
Comparative dynamics and location of chain spin-labelled sphingomyelin and phosphatidylcholine in dimyristoyl phosphatidylcholine membranes studied by ESR spectroscopy
Biochem.Biophys.Acta 1468 ,359-366
Hollmann F, Schmid A, Steckhan E
The first synthetic application of a monooxygenase employing indirect electrochemical NADH regeneration
Angew Chem Int Ed 40(1) 2001, 169-171
Hoormann D, Kubon C, Jörissen J, Pütter H, Kröner L, Steckhan E
Optimierung einer Solid-Polymer-Electrolyte-Zelle für die leitsalzfreie elektroorganische Synthese durch Ermittlung der einzelnen Zellspannungs-Anteile
Elektrochemische Reaktionstechnik und Synthese, GDCh-Monographie Bd. 14 537-543
Hopf A, Dötz KH
Quinone platinum complex catalyzed hydrosilytation of alkenes and alkynes
J Molecular Catalysis A: Chemical 164, 2000, 191-194
Hübner GM, Gläser J, Seel C, Vögtle F
Hocheffiziente Synthese von Rotaxanen mit einem anionischen Templat ; High-Yielding Rotaxane Synthesis with an Anion Template
Angew. Chem. 1999, 111/3, 395-398; Angew. Chem. Int. Ed. Engl. 1999, 38, 383- 386
Hübner GM, Nachtsheim G, Li QY, Seel C, Vögtle F
Zum Raumbedarf von Dendrimeren: das Abfädeln von Rotaxanen; The Spacial Demand of Dendrimers: Deslipping of Rotaxanes
Angew. Chem. 2000, 112, 7, 1315-1318; Angew. Chem. Int. Ed. 2000, 39, 7, 1269-1272
Hübner GM, Reuter C, Seel C, Vögtle F
Rotaxane Synthesis via Nucleophilic Substitution Reaction: The Trapping of Electrophilic Threads by Organic Anion-Wheel Complexes
Synthesis 2000, 1, 103-108
Huwiler A, Kolter T, Pfeilschifter J, Sandhoff K
Physiology and pathophysiology of sphingolipid metabolism and signaling
Biochim.Biophys. Acta 1485 (2000),63-99
Ibach S, Prautzsch V, Vögtle F, Chartroux C, Gloe K
Homocalixarenes
Acc. Chem. Res. 1999, 32, 729-740
Jahn R, Bock A , Breiner KM, Breunig KD, Bujard H, Campos-Ortega J, Ganten D , Grummt I, Gruss P, Goridis C, Huber K, Hoch M, Jackle H, Kahmann R, Koch-Brandt C, Leptin M, Michel H, Noegel A, Neher E, Nusslein-Volhard C, Pfanner N, Sandhoff K, Schoen A, Schwille P, Simons K , Zrenner E
Distinguished scientists back Germany's DFG
NATURE 404: (6781) 922-922
Jäkel C, Dötz KH
Direct metalation of glycals: short and efficient routes to diversely protected stannylated glycals
J Organomet Chem 624, 2001, 172-185
Janes E, Dötz KH
Synthesis of organometallic disaccharides bearing two monosaccharide moietis linked by a chromium carbene spacer
J Organomet Chem 622, 2001, 251-258
Jenne, A., Famulok, M.
Disruption of the Streptavidin Interaction with Biotinylated Nucleic Acid Probes by 2-Mercaptoethanol
BioTechniques, 26, 249-254
Jenne, A., Gmelin, W., Raffler, N., Famulok, M.
Real-time characterization of ribozymes by fluorecence resonance energy transfer (FRET)
Angew. Chem. Int. Ed. 38, 1300-1303
Jenne, A., Hartig, J. S., Piganeau, N., Tauer, A., Samarsky, D. A., Green, M. R., Davies, J., Famulok, M.
Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology
Nature Biotechnol. 19, 56-61
Jonas M, Blechert S, Steckhan E
Photochemically induced electron transfer (PET) catalyzed radical cyclization: A practical method for inducing structural changes in peptides by formation of cyclic amino acid derivatives
J Org Chem 66(21, 2001, 6896-6904
Jonas M, Blechert S, Steckhan E
Photochemically induced electron transfer (PET) catalyzed radical cyclization: A practical method for inducing structural changes in peptides by formation of cyclic amino acid derivatives
Abstract Papers American Chemical Society 221: 126-Orgn, Part 2, 2001
Kase R, Bierfreund U, Klein A, Kolter T, Utsumi K, Itoh K, Sandhoff K, Sakuraba H
Characterization of two a-galactosidase mutants (Q279E and R301Q) found in an atypical variant of Fabry disease
Arch. Biochem. Biophys. Acta 1501 (2000) 227-235
Kauffmann C, Müller WM, Vögtle F, Weinman S, Abramson S, Fuchs B
Rotaxanes with Chiral Stoppers and Photoresponsive Central Unit
Synthesis 1999, 5, 849-853
Kawai H, Allende ML, Wada R, Kono M, Sango K, Deng C, Miyakawa T, Crawley JN, Werth N, Bierfreund U, Sandhoff K, Proia RL
Mice Expressing Only Monosialoganglioside GM3 Exhibit Lethal Audiogenic Seizures
J. Biol. Chem, 276, 6885-6888
Kirchhoff JH, Bräse S, Enders D
A Novel Hydrazine Linker Resin and its Application For the Solid-phase Synthesis of a?branched Primary Amines
J. Comb. Chem. 2001, 3, 71-77
Kirchhoff JH, Lormann MEP, Bräse S
Polymer-bound Auxiliaries for Asymmetric Synthesis on Solid Support: New Approaches to Chiral, Non-racemic Drugs
Chimica Oggi 2001, 10/11, 28-33
Klapdohr S, Dötz KH, Assenmacher W, Hoffbauer W, Hüsing N, Nieger M, Pfeiffer J, Popall M, Schubert U, Trimmel G
Incorporation of Chromium Carbene in a Silica Matrix by Sol-Gel Processing: Application to Aminolysis of Alkoxycarbene Complexes
Chem Eur J 6, 2000, No 16, 3006-3017
Klug, S. J., Hüttenhofer, A., Famulok, M.
In vitro selection of RNA aptamers that bind special elongation factor SelB, a protein with multiple RNA binding sites, reveals one major interaction domain at the carboxy terminus
RNA , 5, 1180-1190
Knoll F, Kolter T, Sandhoff K
Sphingolipid photoaffinity labels
Methods in Enzymology Vol. 311, 2000, 568-600
Kolter T, Döring T, Wilkening G, Werth N, Sandhoff K
Recent advances in the biochemistry of glycosphingolipid metabolism
Biochemical Society Transactions (1999) Volume 27, part 4, 409:415.
Kolter T, Magin T, Sandhoff K
Biomolecule Function: No Reliable Prediction from Cell Culture
Traffic 2000 1: 803-804
Kolter T, Sandhoff K
Sphingolipide- Stoffwechselwege und die Pathobiochemie neurodegenerativer Erkrankungen
Angew. Chem. 1999,111, 1632-1670
Kolter T, Sandhoff K
Sphingolipids -Their Metabolic Pathways and the Pathobiochemistry of Neurodegenerative Diseases
Angew. Chem. Int. Ed. 1999, 38, 1532-1568
Kolter T, Sandhoff K
Sphingolipide- Stoffwechselwege und die Pathobiochemie neurodegenerativer Erkrankungen
Angew. Chem. 1999,111, 1632-1670
Kolter T, Sandhoff K
Sphingolipids- Their metabolic Pathways and the Pathobiochemistry of Neurodegenrative Diseases
Angew. Chem. Int.Ed. 1999, 38, 1532-1568
Kolter T, Sandhoff K
Sphingolipidosen
Handbuch der Molekularen Medizin Bd. 6, 1999, 195-234
Kolter T, Sandhoff K
Lysosomal Degradation of Glycolipids
Carbohydrates Vol 2, Ernst/Hart/ Sinay, Wiley-VCH, (2000), 453-472
Kolter T, Sandhoff K
Animal Glycolipids: Biosynthesis and degradation
Glycoscience: Chemistry and Chemical Biology III, Chapter 7.4, 2149 - 2182, Springer, Berlin, 2001
Krebs AW, Thölke B, Pforr K-I, König WA, Scharwächter K, Grimme S, Vögtle F, Sobanski A, Schramm J, Hormes J
Synthesis of enantiomerically pure (E)-1,1,3,3,6,6,-hexamethyl-1-sila-4-cycloheptene and its absolute configuration
Tetrahedron Assymm. 1999 10, 3483 - 3492
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Leitsalzfreie elektrochemische Oxidation von Ethern
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Langmann T, Büchler C, Ries S, Schäffler AC , Schuirer MA, Weiler M, Sandhoff K, DeJong PJ, Schmitz G
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J. Lipid Res., 40(5), 870-880
Langmann T, Büchler C, Ries S, Schäffler AC, Schuirer MA, Weiler M, Sandhoff K, DeJong PJ, Schmitz G
Transcription factors Sp1 and AP-2 mediate induction of acid sphingomyelinase during monocytic differentiation
J. Lipid Res., 40(5), 870-880
Lansmann S, Bartelsen O, Sandhoff K
Purification and characterisation of recombinant human acid sphingomyelinase expressed in insect Sf21 cells
Methods in Enzymology Vol. 311, 2000, 149-156
Lazny R, Poplawski J, Köbberling J , Enders D , Bräse S
Triazenes: A Useful Protecting Strategy for Sensitive Secondary Amines
Synlett 1999, 1304-1306
Lazny R, Sienkiewicz M, Bräse S
Application of Triazenes for protection of secondary amines
Tetrahedron 2001, 57, 5825-5832
Lennartz M, Sadakane M, Steckhan E
Electrochemical oxidation of (R)-4-hydroxy-2-pyrrolidone: A key building block for stereoselective N-acyliminium ion coupling reactions
Tetrahedron 55(50) 1999, 14407-14420
Lennartz M, Steckhan E
Synthesis of bicyclic lactams via ring closing olefin metathesis and intramolecular Heck reaction
Synlett (3) 2000, 319-322
Lennartz M, Steckhan E
A chiral hexahydroindolizine as key intermediate in the synthesis of tri- and tetrahydroxyindolizidines
Tetrahedron 57(4) 2001, 675-680
Li, CM , Park JH, He X, Levy B, Chen F, Arai K, Adler DA, Disteche CM, Koch J, Sandhoff K, Schuchman EH
The Human Acid Ceramidase Gene (ASAH): Structure, Chromosomal Location, Mutation Analysis, and Expression
Genomics 1999 Dec 1; 62(2):223-231
Linke T, Lansmann S, Sandhoff K
Purification of acid ceramidase from human placenta
Methods in Enzymology Vol. 311, 2000, 201-207
Linke T, Wilkening G, Lansmann S, Moczall H, Bartelsen O, Weisgerber J, Sandhoff K
Stimulation of Acid Sphingomyelinase Activity by Lysosomal Lipids and Sphingolipid Activator Proteins
Biol.Chem. 382, 283-290
Linke T, Wilkening G, Sadeghlar F, Moczall H, Bernardo K, Schuchman E, Sandhoff K
Interfacial Regulation of Acid Ceramidase Activity: Stimulation of Ceramide Degradation by Lysosomal Lipids and Sphingolipid Activator Proteins
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Li QY, Vogel E, Parham AH, Nieger M, Bolte M, Fröhlich R, Saarenketo P, Rissanen K, Vögtle F
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Eur. J. Org. Chem. 2001, 4041-4049
Liu A, Wada R, Kawai H, Sango K, Deng C, Tai T, McDonald MP, Araujo K, Crawley JN, Bierfreund U, Sandhoff K, Suzuki K, Proia L
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Lormann M, Dahmen S, Bräse S
Hydro-dediazoniation of Diazonium Salts using Trichlorosilane: New Cleavage Conditions for the T1 Traceless Linker
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Meents A, Barbier B, Euler H, Kirfel A, Schwierz H, Vögtle F
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Z. Kristallogr. NCS 2000, 215, 115-116
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Rationales Design von niedermolekularen Organogelatoren: auf dem Weg zu einer Bibliothek von funktionellen N-Acyl-1,w-Aminosäure-Derivaten; Rational Design of Low Molecular Mass Organogelators: Toward a Library of Functional N-Acyl-1,ω-Amino Acid Derivatives
Angew. Chem. 2001, 113, 17, 3266-3267; Angew. Chem. Int. Ed. 2001, 40, No. 17, 3164-3166
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Gangliosidosis are Transported from the Plasma Membrane to Intralysosomal Membranes as Revealed by Immuno-Electron Microscopy
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Study on formation and stability of azacage metal complexes using electrospray mass spectrometry
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Darstellung und Atropisomerie von 1-(2-Aryl)-piperidin-2-onen
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Synthesis 1999, 10, 1753-1758
Mohry A, Vögtle F, Nieger M, Hupfer H
Regioselective Template Synthesis, X-Ray Structure, and Chiroptical Properties of a Topologically Chiral Sulfonamide Catenane
Chirality 2000, 12, 76-83
Moretó JM, Ricart S, Dötz KH, Molins E
Reaction of Alkynyl Alkoxy Metal Carbene Complexes with 1,2-Diamines
Organometallics 20, 2001, 62-70
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Acid Ceramidase Deficiency: Farber Lipogranulomatosis
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Chem. Eur. J. 1999, 5, 2584-2601
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Tetrahedron: Asymmetry 1999, 10, 2153-2164
Nieger M, Haase WC, Dötz KH
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Acta Cryst C56, 2000, e174-e175
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Acta Cryst C56, 2000, e390-e391
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Catalyzed Nucleophilic Substitution on Cyclopropenylmethyl Esters - Reactions via a 1,2-Methano-p-allylpalladium Intermediate
Synlett 2000, 1467-1469
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FASEB J. 2001 Jun;15(8):1475-1477
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Synlett 1999, 12, 1887-1890
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Chemical Reactions in the Axle of Rotaxanes - Steric Hindrance by the Wheel
Eur. J. Org. Chem. 1999, 1233-1238
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Continuous indirect electrochemical regeneration of galactose oxidase
Bioorgan Med Chem 7(10) 1999, 2203-2208
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Cleavage of Immobilised Disubstituted Triazenes with Electrophiles: Synthesis of Alkyl Halides and Esters with Polymer-bound Reagents
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Plevoets M, Vögtle F, De Cola L, Balzani V
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Quantification of mRNAs encoding proteins of the glycosphingolipid catabolism in mouse models of GM2 gangliosidoses and sphingolipid activator protein precursor (prosaposin) deficiency
Biochem.Biophys.Acta 1502, 391-397
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Analysis of the Structure of Dendrimers in Solution by Small-Angle Neutron Scattering Including Contrast Variation
Macromolecules 1999, 32, 4079-4087
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The structure of dendritic molecules in solution as investigated by small-angle neutron scattering
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[1]Rotaxanes and Pretzelanes: Synthesis, Chirality, and Absolute Configuration
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Reuter C, Schmieder R, Vögtle F
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ReuterC, Seel C, Nieger M, Vögtle F
Chiral [1]Rotaxanes: X-Ray Structures and Chiroptical Properties
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Reuter C, Vögtle F
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Reuter C, Wienand W, Hübner GM, Seel C, Vögtle F
High-Yield Synthesis of Ester, Carbonate, and Acetal Rotaxanes by Anion Template Assistance and their Hydrolytic Dethreading
Chem.Eur.J. 1999, 5, No. 9, 2692-2697
Reuter C, Wienand W, Schmuck C, Vögtle F
A Self-Threaded "Molecular 8"
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Romiti E, Vasta V, Meacci E, Farnararo M, Linke T, Ferlinz K, Sandhoff K, Bruni P
Characterization of sphingomyelinase activity released by thrombin-stimulated platelets
Mol. Cell Biochem, 205:(1-2) 75-81
Rossler U, Blechert S, Steckhan E
Single electron transfer induced total synthesis of canthin-6-one
Tetrahedron Lett 40(39) 1999, 7075-7078
Sadakane M, Steckhan E
Co-solvent effects on the redox potentials of manganese-substituted alpha-Keggin-type silicon polyoxotungstate : First electrochemical generation of the manganese(V)redox system in an aqueous environment
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Sadeghlar F, Sandhoff K, van Echten-Deckert G
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Ein molekularer Knoten mit zwölf Amidgruppen - Einstufensynthese, Kristallstruktur, Chiralität; A Molecular Knot with Twelve Amide Groups - One-Step Synthesis, Crystal Structure, Chirality
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Safarowsky O, Vogel E, Vögtle F
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GM2 gangliosidosis AB variant - Clinical and biochemical studies of a Japanese patient
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On the Way to Rotaxane-Based Molecular Motors: Studies in Molecular Mobility and Topological Chirality
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Characterization of Regulatory Elements in the 5´-Flanking Region of the GM2 Activator Gene
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Electrogenerated chiral 4-methoxy-2-oxazolidinones as diastereoselective amidoalkylation reagents for the synthesis of beta amino alcohol precursors
Eur J Org Chem 13, 2001, 2425-2433
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Molecular Threading - Chemical Structures Held Together by Mechanical Bonds
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The Glycosphingolipidoses - from Disease to basic Principles of Metabolism
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Die Glykosphingolipidoesn - von Krankheiten zu Prinzipien des Stoffwechsels
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Complete analysis of the glycosylation and disulfide bond pattern of human beta-hexosaminidase B by MALDI-MS
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Amide-Based Oligocatenanes by an Iterative Template Strategy
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New Porphyrinoid Di-imines by Cyclization of 1,9-Bis(5-formylpyrrol-2-yl)dipyrrins withNew Porphyrinoid Di-imines by Cyclization of 1,9-Bis(5-formylpyrrol-2-yl)dipyrrins with Arene-1,2-diimines and Hydrazines
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Novel RNA catalysts for the Michael reaction
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Synthesis and Host-Guest Properties of Multi-Crown Dendrimers towards Sodium Pertechnetate and Mercury(II) Chloride
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pH-Controlled Inclusion and Release of Oxyanions by Dendrimers Bearing Methyl Orange Moities
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Comprehensive Natural Product Chemistry, Chapter 3.05, 87-106
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Comprehensive Natural Product Chemistry, Chapter 3.05, 87-106
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Vögtle F, Hünten A, Vogel E, Buschbeck S, Safarowsky O, Recker J, Parham AH, Knott M, Müller WM, Müller U, Okamoto Y, Kubota T, Lindner W, Francotte E, Grimme S
Neue molekulare Knoten mit Amidstruktur: vollständige Enantiomerentrennung, chiroptische Eigenschaften, absolute Konfiguration; Novel Amide-Based Molecular Knots: Complete Enantiomeric Separation, Chiroptical Properties, and Absolute Configuration
Angew. Chem. 2001, 113, 13, 2534-2537; Angew. Chem. Int. Ed. 2001, 40/13, 2468-2471
Vögtle F, Plevoets M, Nieger M, Azzellini GC, Credi A, De Cola L, De Marchis V, Venturi M, Balzani V
Dendrimers with a Photoactive and Redox-Active [Ru(bpy)32+-Type Core: Photophysical Properties, Electrochemical Behavior, and Excited-State Electron-Transfer Reactions
J. Am. Chem. Soc. 1999, 121, 6290-6298
Vögtle F, Prautzsch V, Chartroux C, Gloe K
A Palladium(II) Selective Complexing Agent Based on the all-Homocalixarene Skeleton
Supramol. Chem. 1999, 11, 93-96
Vögtle F, Safarowsky O, Heim C, Affeld A, Braun O, Mohry A
Catenanes, rotaxanes and pretzelanes - template synthesis and chirality
Pure & Appl. Chem. 1999, 71, 2, 247-251
Vögtle F, Udelhofen D, Abramson S, Fuchs B
Photoresponsive lower-rim azobenzene substituted and bridged calix[4]arenes
J. Photochemistry and Photobiology A: Chemistry 2000, 131, 41-48
Waldmann, H., Famulok, M.
Editorial 2001.
ChemBioChem 2, 3-6.
Wamhoff H, Bamberg A, Sohár P
Efficient Synthesis of Fused Isothiazolo C-Nucleosides, III. Synthesis of 7-substituted Isothiazolo[4,5-d]pyrimidine C-Nucleosides.
Nucleosides, Nucleotides & Nucleic Acids 20(3) (2001) 229-241
Wamhoff H, Höhmann C, Sohár P
An Efficient Synthesis of Thioisomünchnones Derived from Uracils and Uridine: Novel Type of Mesoionic Nucleosides.
Organic Letters 2(5) (2000) 581-584
Wamhoff H, Muhr J, Horn M, Sohár P, Csámpai A
Reactions of Uracils, 23. Subsequent Reaction of 7-Ethoxypyrimido[4,5-d]pyrimidines: Nucleophilic Exchange, Pyrimido[4,5:4'5']pyrimido[1,2-a]quinazolines, Benzo[f]pyrimido[4,5:4',5']pyrimido[1,2-d][1,3,4]triazepine.
Heterocyclic Communications 5(4) (1999) 365-376
Wamhoff H, Sattler C, Sohár P, Rohonczy J
Reactions of Uracils, 24. Multiple Anellation to Uracils an their Analogs - An Approach to Nevirapine-Type Tricycles.
Synth Commun 29(22) (1999) 3919-3937
Wamhoff H, Scheider V
Photodegradation of Imidacloprid.
J Agric Food Chem 47 (1999) 1730-1734
Wamhoff H, Warnecke H
Synthesis and Cycloaddition Reactions of [2-Deoxy-3,5-bis-O-(p-toluoyl)-alpha-D-ribofuranosyl]ethyne.
Arkivoc 2(2)(2001) 1085-1090
Wendeler M, Sandhoff K, Kolter T
Pathology of sphingolipid metabolism: The molecular and cellular basis of neurodegenerative disease
The Neuroscientist, 6(4) 285-296, 2000
Werth N, Schuette C, Wilkening G, Lemm T, Sandhoff K
Degradation of Membrane-Bound Ganglioside GM2 by b- Hexosaminidase A: Stimulation by GM2 Activator Protein and Lysosomal Lipids
J. Biol. Chem., 276, 12685-12690
Weyershausen B, Dötz KH
Novel Approach to 6- Chromanols via Photochemical Benzannulation of alpha-exo-Benzylidene 2-oxacyclohexylidene Chromium Complexes
Synlett 1999, 231-233
Weyershausen B, Dötz KH
Cycloisomerization of Alkynols at Transition Metal Templates
Eur J Inorg Chem, 1999, 1057-1066
Weyershausen B, Nieger M, Dötz KH
Stereospecific exo-Selective Diels-Adler Reactions with Carbohydrate-Functionalized alpha-exo-Methylene-2-oxacyclopentylidene Chromium Complexes
J Org Chem 64,1999, 4206-4210
Weyershausen B, Nieger M, Dötz KH
Organotransition metal-modified sugars Part 16. Diastereoselective synthesis of carbohydrate-derived spirocyclic 2-oxacyclohexylidene chromium and tungsten complexes
J Organomet Chem 602, 2000, 37-44
Wilkening G, Linke T, Uhlhorn-Dierks G, Sandhoff K
Degradation of Membrane-Bound Ganglioside GM1: Stimulation by Bis(monoacylglycero)phosphate and the Activator Proteins SAP-B and GM2-AP
J. Biol. Chem., 275, (46), 35814-35819
Windisch B, Vögtle F, Nieger M, Lahtinen T, Rissanen K
Macrocyclic Hydrocarbons with Rigid and Flexible Building Blocks
J. Prakt. Chem. 2000, 342, 642-653
Wörsdörfer U, Vögtle F, Glorius F, Pfaltz A
A New Planar Chiral Bipyridine-Ligand: Pyrid-2-yl[2](1,4)benzeno[2](5,8)quinolino-phane
J. Prakt. Chem. 1999, 341, 5, 445-448
Wörsdörfer U, Vögtle F, Nieger M, Waletzke M, Grimme S, Glorius F, Pfaltz A
A New Planar Chiral Bipyridine Ligand
Synthesis 1999, 4, 597-602
Wrobe D, Henseler M, Hüttler S, Pascual SI , Chabas A, Sandhoff K
An non-glycosylated and functionally deficient mutant (N215H) of the sphingolipid activator protein B (SAP-B) in a novel case of metachromatic leukodystrophy (MLD)
J. of Inher. Metab. Dis. 23 (2000) 63-76
Yamashita T, Wada R, Sasaki T, Deng C, Bierfreund U, Sandhoff K, Proia RL
A vital role for glycosphingolipid synthesis during development and differentiation
J.Histochem.Cytochem.1999 Aug. 47(8): 1005-1014
Zelgert M, Lennartz M, Steckhan E
Two directional electroorganic synthesis - electrochemical oxidation and application of a C-2-symmetric building block
Tetrahedron 58(13) 2002, 2641-2646
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